NanoString’s CosMx Spatial Molecular Imager was named a Top 10 Innovation of 2022 by The Scientist Magazine

SEATTLE–(BUSINESS WIRE)–NanoString Technologies, Inc. (NASDAQ: NSTG), a leading provider of life science tools for discovery and translational research, today announced that the company’s CosMx™ Spatial Molecular Imager (SI) has been recognized by The scientist Magazine as one of the top 10 innovations of 2022 (https://www.the-scientist.com/ts-digest/view/the-scientist-top-10-innovations-2022-12-2). This recognition identifies CosMx SMI as a product poised to revolutionize research and advance scientific knowledge, with the potential to advance rapid advances and address specific problems in their respective fields.

CosMx SMI enables high-resolution imaging of more than 1,000 RNA and over 64 protein analytes in morphologically intact whole tissue sections. The CosMx instrument enables researchers to visualize and quantify gene and protein expression at single-cell and subcellular resolutions in both fresh-frozen and formalin-fixed paraffin-embedded (FFPE) tissue samples. Using a multimodal approach including protein imaging, CosMx SMI delivers best-in-class cell segmentation. With high-plex in situ analysis, researchers can perform cell typing, cell state, functional, and cell-cell interaction analysis in a single experiment to create high-resolution cell atlases.

“The CosMx SMI is the only tool that gives us the ability to visualize thousands of genes simultaneously at subcellular resolution and across all cells in a tissue,” said Miranda Orr, PhD, an Alzheimer’s researcher at Wake Forest University School of Medicine in North Carolina, which purchased both CosMx SMI and GeoMx Digital Spatial Profiler (DSP) from NanoString. “We are able to develop maps of the brain with unprecedented resolution.”

CosMx SMI serves scientists from across the research continuum with an adjustable workflow that can prioritize either high-plexus, unbiased whole-slide imaging for discovery or high-throughput biology-driven analysis for translational research applications. Researchers can choose from a variety of CosMx SMI assays, including predefined panels, predefined panels combined with custom content, or fully custom assays supporting studies of any species.

The CosMx SMI is the latest product in the company’s industry-leading spatial analysis portfolio and complements the GeoMx® DSP. The GeoMx DSP is a fully automated spatial profiler that enables multicellular analysis of the entire transcriptome for both human and mouse applications. Both platforms are also adaptable for other species.

To learn more about NanoString’s CosMx Spatial Molecular Imager, visit www.nanostring.com/CosMx

About NanoString Technologies, Inc.

NanoString Technologies, a leader in spatial biology, provides an ecosystem of innovative discovery and translational research solutions that enable our customers to map the biology universe. Cited in more than 170 peer-reviewed publications, the GeoMx® Digital Spatial Profiler is a flexible and consistent solution that combines the power of whole-tissue imaging with gene expression and protein data for total spatial transcriptomics and proteomics from an FFPE slide. The CosMx™ Spatial Molecular Imager is a FFPE-compatible single-cell imaging platform based on spatial multiomics that enables researchers to map single cells in their natural environment to gain deep biological insights and novel discoveries from an experiment. The AtoMx™ Spatial Informatics Platform is a cloud-based informatics solution with advanced analytics and global collaboration capabilities that enables powerful insights into spatial biology anytime, anywhere. The foundation of our research tools is our nCounter® analysis system, which is cited in more than 6,000 peer-reviewed publications and offers a safe way to profile the expression of hundreds of genes, proteins, miRNAs or copy number variations simultaneously with high sensitivity and precision. Visit www.nanostring.com for more information.

NanoString, NanoString Technologies, the NanoString logo, CosMx, GeoMx, AtoMx, and nCounter are trademarks or registered trademarks of NanoString Technologies, Inc. in various jurisdictions.

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